SPINA 4.0.1

SPINA is software for determining constant structure-parameters of endocrine feedback control systems from hormone levels obtained in vivo. The first version of this cybernetic approach (SPINA Thyr) allows for evaluating the functional status of the thyroid gland, i.e. thyroid's secretory capacity (SPINA-GT) and sum activity of peripheral deiodinases (SPINA-GD). Additional structure parameters that are calculated include Jostel's TSH index and TTSI.