Natron is a visual effects composition software. It supports many common image file formats (EXR, DPX, TIFF, JPEG, PNG); colorspace management via OpenColorIO, and visual effects via OpenFX / OFX plugins. It has low hardware requirements that allow real-time playback, comes with command line tools, and uses Python3 for scripting.
Pydiogment aims to simplify audio augmentation. It generates multiple audio files based on a starting mono audio file. The library can generates files with higher speed, slower, and different tones etc.
Calf Studio Gear is a stack of audio effect plugins for JACK sound servers and LV2 hooks. It contains instruments and tone generators, dynamic processors, digital effects, modulators, filters and equalizers, delay effects, distortion and enhancement filters, as well as some tools aimed at professionals.